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Sag, AA; Brody, LA; Maybody, M; Erinjeri, JP; Wang, X; Wimmer, T; Silk, M; Petre, EN; Solomon, SB.
Acute and delayed bleeding requiring embolization after image-guided liver biopsy in patients with cancer.
Clin Imaging. 2016; 40(3):535-540
Doi: 10.1016/j.clinimag.2015.11.004
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- Co-Autor*innen der Med Uni Graz
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Wimmer Thomas
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- Abstract:
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To report incidence of acute versus delayed presentations of bleeding requiring embolization after focal liver biopsy, in correlation with angiographic findings and treatment success rates. The available literature will be reviewed as well.
Health Insurance Portability and Accountability Act-compliant institutional review board approved retrospective review of 2180 consecutive patients undergoing 2335 targeted liver biopsies at a tertiary-care cancer center. Hepatic arterial embolization episodes within 30days from biopsy were identified via radiology PACS. Electronic medical record review was performed for indication of embolization and postembolization clinical course.
The incidence of postbiopsy bleeding requiring embolization was 0.5% (12/2335 biopsies). In those with bleeding, 1/12 (8%) had no hepatic arterial findings at angiography. Angiographic hepatic arterial findings resolved after embolization in 11/11 patients (100% technical success). Bleeding ceased after embolization in 10/12 patients (83% clinical success). Complications were seen in 2/12 (17%) patients: cholecystitis and hepatic infarct, respectively. Delayed presentation of bleeding (defined as >24h postbiopsy) occurred in 5/12 (42%) patients; the longest latency was 12days.
The overall incidence of bleeding requiring embolization in our population was 0.5%. This complication rate compares favorably to the 0-4.2% (median: 0.29%) rate quoted in the available, heterogeneous, literature on this topic. Delayed presentation occurred in almost half of patients. Arterial embolization carries excellent technical and clinical success rates.
Copyright © 2016 Elsevier Inc. All rights reserved.
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Adult -
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Aged -
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Embolization, Therapeutic -
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Female -
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Hemorrhage - diagnostic imaging
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Hemorrhage - epidemiology
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Hemorrhage - etiology
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Hemorrhage - therapy
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Hepatic Artery - diagnostic imaging
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Humans -
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Image-Guided Biopsy - adverse effects
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Incidence -
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Liver - diagnostic imaging
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Liver - pathology
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Liver Diseases - diagnostic imaging
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Liver Diseases - epidemiology
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Liver Diseases - etiology
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Liver Diseases - therapy
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Liver Neoplasms - pathology
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Male -
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Middle Aged -
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Retrospective Studies -
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Time Factors -
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Treatment Outcome -
- Find related publications in this database (Keywords)
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Image-guided biopsy
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Hemorrhage
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Embolization, Therapeutic
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Radiology, Interventional