Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Marsoner, K; Kornprat, P; Sodeck, G; Schagerl, J; Langeder, R; Csengeri, D; Wagner, D; Mischinger, HJ; Haybaeck, J.
Pancreas Cancer Surgery in Octogenarians - Should We or Should We Not?
Anticancer Res. 2016; 36(4):1979-1984
Web of Science
PubMed
- Führende Autor*innen der Med Uni Graz
- Kornprat Peter
- Marsoner Katharina
- Co-Autor*innen der Med Uni Graz
- Csengeri Dora
- Haybäck Johannes
- Mischinger Hans-Jörg
- Wagner Doris
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- Abstract:
- In this study we aimed to determine if advanced age represents a risk factor for negative perioperative and long-term outcome in patients undergoing curative surgery ductal pancreatic adenocarcinoma surgery. Two-hundred-twenty-one consecutive patients, twelve (6%) patients ≥80 years were included in the study. We assessed perioperative and long-term outcome and independent predictors for in-hospital mortality with Cox regression analysis. Advanced age was not a predictor for in-hospital mortality (6.3% in non-octogenarian versus 8.3% in octogenarians; p=0.55) nor for morbidity (31% vs. 32%; p=0.69). An ASA score >II was the only predictor for in-hospital mortality (odds ratio (OR)=10.10, 95%CI=1.28-79.60; Hosmer-Lemeshow: p=0.86). No significant difference was observed in one- and five-year survival rates (68 and 58% vs. 16 and 14%; log-rank p=0.61). Advanced age is not a risk factor for negative outcome in curative pancreatic cancer surgery. Therefore, this single curative option should be considered in octogenarians at risk. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Aged, 80 and over -
- Female -
- Hospital Mortality -
- Humans -
- Kaplan-Meier Estimate -
- Male -
- Middle Aged -
- Pancreatectomy - mortality
- Pancreatic Neoplasms - mortality
- Pancreatic Neoplasms - surgery
- Postoperative Complications - mortality
- Regression Analysis -
- Risk Factors -
- Treatment Outcome -
- Find related publications in this database (Keywords)
- Pancreatic ductal adenocarcinoma
- pancreatic resection
- perioperative risk
- octogenarians vs. non -octogenarians
- short-term outcome
- long-term outcome