Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sadekova, ON; Nikitina, LA; Rashidov, TN; Voloschuk, IN; Samokhodskaya, LM; Demidova, EM; Tkachuk, VA.
Luteal phase defect is associated with impaired VEGF mRNA expression in the secretory phase endometrium.
Reprod Biol. 2015; 15(1):65-68
Doi: 10.1016/j.repbio.2014.10.001
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Nikitina Liudmila
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- Abstract:
- Endometrial morphology and expression of vascular endothelial growth factor (VEGF) was examined in the endometria of women with history of recurrent miscarriage (RM group) and of fertile women without history of gynecological diseases (control group). Luteal phase defect (LPD) was diagnosed in 42% cases in the RM group vs. 13% in controls. Endometrial VEGF mRNA expression was lower in LPD endometria compared to mature endometria. In conclusion, LPD in non-pregnant endometrium is associated with angiogenic abnormalities and may cause pregnancy complications. Copyright © 2014 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Endometrium - metabolism
- Female -
- Gene Expression Regulation - physiology
- Humans -
- Luteal Phase - physiology
- Pregnancy -
- RNA, Messenger - genetics RNA, Messenger - metabolism
- Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism
- Find related publications in this database (Keywords)
- LPD
- Endometrium
- Angiogenesis
- VEGF
- Recurrent miscarriage