Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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SHR Neuro Krebs Kardio Lipid Stoffw Microb
Baron, DM; Hochrieser, H; Posch, M; Metnitz, B; Rhodes, A; Moreno, RP; Pearse, RM; Metnitz, P; European Surgical Outcomes Study (EuSOS) group for Trials Groups of European Society of Intensive Care Medicine; European Society of Anaesthesiology.
Preoperative anaemia is associated with poor clinical outcome in non-cardiac surgery patients.
Br J Anaesth. 2014; 113(3): 416-423.
Doi: 10.1093/bja/aeu098
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- Führende Autor*innen der Med Uni Graz
- Metnitz Philipp
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- Abstract:
- Retrospective studies suggest that preoperative anaemia is associated with poor outcomes after surgery. The objective of this study was to describe mortality rates and patterns of intensive care resource use for patients with anaemia undergoing non-cardiac and non-neurological in-patient surgery. We performed a secondary analysis of a large prospective study describing perioperative care and survival in 28 European nations. Patients at least 16 yr old undergoing in-patient surgery during a 7 day period were included in the study. Data were collected for in-hospital mortality, duration of hospital stay, admission to intensive care, and intensive care resource use. Multivariable logistic regression analysis was performed to understand the effects of preoperative haemoglobin (Hb) levels on in-hospital mortality. We included 39 309 patients in the analysis. Preoperative anaemia had a high prevalence in both men and women (31.1% and 26.5%, respectively). Multivariate analysis showed that patients with severe [odds ratio 2.82 (95% confidence interval 2.06-3.85)] or moderate [1.99 (1.67-2.37)] anaemia had higher in-hospital mortality than those with normal preoperative Hb concentrations. Furthermore, hospital length of stay (P<0.001) and postoperative admission to intensive care (P<0.001) were greater in patients with anaemia than in those with normal Hb concentrations. Anaemia is common among non-cardiac and non-neurological surgical patients, and is associated with poor clinical outcome and increased healthcare resource use. NCT01203605 (ClinicalTrials.gov). © The Author [2014]. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
- Find related publications in this database (using NLM MeSH Indexing)
- Anemia - epidemiology
- Causality -
- Cohort Studies -
- Comorbidity -
- Critical Care - statistics & numerical data
- Critical Care - epidemiology
- Female -
- Hospital Mortality -
- Humans -
- Intensive Care Units - statistics & numerical data
- Length of Stay - statistics & numerical data
- Male -
- Middle Aged -
- Odds Ratio -
- Outcome and Process Assessment (Health Care) - statistics & numerical data
- Postoperative Complications - epidemiology
- Preoperative Period -
- Prospective Studies -
- Risk Factors -
- Surgical Procedures, Operative - statistics & numerical data
- Find related publications in this database (Keywords)
- anaemia
- assessment, outcome
- care, intensive
- epidemiologic studies, cohort studies
- mortality determinants