Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sturmberger, L; Wallace, PW; Glieder, A; Birner-Gruenberger, R.
Synergism of proteomics and mRNA sequencing for enzyme discovery.
J Biotechnol. 2016; 235(2):132-138
Doi: 10.1016/j.jbiotec.2015.12.015
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- Führende Autor*innen der Med Uni Graz
- Birner-Grünberger Ruth
- Co-Autor*innen der Med Uni Graz
- Wallace Pal William
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- Abstract:
- Enzyme catalyzed processes are increasingly complementing chemical manufacturing as new enzymes are being discovered. Although, many industrially applied biocatalysts have been identified by functional screenings technological advances in the omics fields have created a different path to access novelty. Here we describe how omics technologies, especially proteomics and transcriptomics, can complement each other in the aim of finding new enzymatic functions. Special emphasis is laid on how mRNA sequencing Zcan improve proteomic experiments by allowing the generation of high quality protein sequence databases, which subsequently facilitates protein identification. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Biotechnology -
- Databases, Nucleic Acid -
- Enzymes - genetics
- Enzymes - metabolism
- Gene Expression Profiling - methods
- Proteomics - methods
- RNA, Messenger - analysis
- RNA, Messenger - genetics
- RNA, Messenger - metabolism
- Sequence Analysis, RNA - methods
- Find related publications in this database (Keywords)
- Enzyme discovery
- Proteomics
- Transcriptomics
- Database
- Biotechnology