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Prattes, J; Raggam, RB; Vanstraelen, K; Rabensteiner, J; Hoegenauer, C; Krause, R; Prüller, F; Wölfler, A; Spriet, I; Hoenigl, M.
Chemotherapy-Induced Intestinal Mucosal Barrier Damage: a Cause of Falsely Elevated Serum 1,3-Beta-d-Glucan Levels?
J Clin Microbiol. 2016; 54(3):798-801
Doi: 10.1128/JCM.02972-15
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- Führende Autor*innen der Med Uni Graz
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Hönigl Martin
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Prattes Jürgen
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Raggam Reinhard Bernd
- Co-Autor*innen der Med Uni Graz
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Hoegenauer Christoph
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Krause Robert
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Prüller Florian
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Rabensteiner Jasmin
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Wölfler Albert
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- Abstract:
- Blood citrulline and intestinal fatty acid binding protein were determined as biomarkers for intestinal mucositis. Biomarker levels were correlated with corresponding serum 1,3-beta-D-glucan levels in 56 samples obtained from 33 cases with underlying hematological malignancies receiving induction chemotherapy. No correlation between biomarkers of intestinal mucositis and BDG levels was observed. (This study has been registered at ClinicalTrials.gov under registration no. NCT01576653.).
- Find related publications in this database (using NLM MeSH Indexing)
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Adult - administration & dosage
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Aged - administration & dosage
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Antineoplastic Agents - adverse effects, therapeutic use
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Biomarkers - administration & dosage
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False Positive Reactions - administration & dosage
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Female - administration & dosage
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Hematologic Neoplasms - complications, drug therapy
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Humans - administration & dosage
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Intestinal Mucosa - drug effects, pathology
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Male - administration & dosage
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Middle Aged - administration & dosage
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Mucositis - blood, diagnosis, etiology
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Sensitivity and Specificity - administration & dosage
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Young Adult - administration & dosage
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beta-Glucans - blood