Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Reischies, FM; Raggam, RB; Prattes, J; Krause, R; Eigl, S; List, A; Quehenberger, F; Strenger, V; Wölfler, A; Hoenigl, M.
Urine Galactomannan-to-Creatinine Ratio for Detection of Invasive Aspergillosis in Patients with Hematological Malignancies.
J Clin Microbiol. 2016; 54(3):771-774
Doi: 10.1128/JCM.02969-15
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- Führende Autor*innen der Med Uni Graz
- Hönigl Martin
- Reischies-Meikl Frederike Marie Josefine
- Co-Autor*innen der Med Uni Graz
- Eigl Susanne
- Krause Robert
- Prattes Jürgen
- Quehenberger Franz
- Raggam Reinhard Bernd
- Strenger Volker
- Wölfler Albert
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- Abstract:
- Galactomannan (GM) testing of urine specimens may provide important advantages, compared to serum testing, such as easy noninvasive sample collection. We evaluated a total of 632 serial urine samples from 71 patients with underlying hematological malignancies and found that the urine GM/creatinine ratio, i.e., (urine GM level × 100)/urine creatinine level, which takes urine dilution into account, reliably detected invasive aspergillosis and may be a promising diagnostic tool for patients with hematological malignancies. (This study has been registered at ClinicalTrials.gov under registration no. NCT01576653.). Copyright © 2016, American Society for Microbiology. All Rights Reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Aspergillosis - diagnosis
- Aspergillosis - etiology
- Aspergillosis - urine
- Biomarkers -
- Creatinine - blood
- Creatinine - urine
- Female -
- Hematologic Neoplasms - complications
- Humans -
- Male -
- Mannans - blood
- Mannans - urine
- Middle Aged -
- ROC Curve -
- Reproducibility of Results -