Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kränke, B; Schuster, C.
Contact dermatitis: relevant differential diagnoses, simulators, and variants.
J Dtsch Dermatol Ges. 2015; 13(11):1073-1088
Doi: 10.1111/ddg.12803
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- Führende Autor*innen der Med Uni Graz
- Kränke Birger
- Co-Autor*innen der Med Uni Graz
- Schuster Christian Josef
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- Abstract:
- Similar to all eczematous disorders, irritant and allergic contact dermatitis are primarily defined by their morphology. In addition, the diagnosis of this specific reaction pattern on the skin (and mucous membranes) also requires prior exposure (direct or indirect) to an allergen or irritant. While it is quite easy to give a textbook description of the typical features of eczema, its clinical manifestations in daily practice are diverse and frequently uncharacteristic. Contact reactions may present as lichenoid, lymphomatoid, granulomatous, pigmented, purpuric, and erythema multiforme-like lesions, thus lacking the typical eczematous appearance and broadening the spectrum of differential diagnoses to be considered. Moreover, a considerable number of agents, acting by mechanisms other than contact, may trigger adverse reactions mimicking the eczematic morphology and distribution pattern of contact dermatitis. Increasingly used in oncology, this is especially true for drugs such as kinase inhibitors. Knowledge of these associations is crucial for the adequate diagnostic and therapeutic care of patients with supposed or actual contact dermatitis. © 2015 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.
- Find related publications in this database (using NLM MeSH Indexing)
- Dermatitis, Contact - diagnosis
- Dermatitis, Contact - therapy
- Diagnosis, Differential -
- Drug Eruptions - diagnosis
- Drug Eruptions - therapy
- Humans -
- Skin Tests - methods