Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Ling, H; Krassnig, L; Bullock, MD; Pichler, M.
MicroRNAs in Testicular Cancer Diagnosis and Prognosis.
Urol Clin North Am. 2016; 43(1):127-134
Doi: 10.1016/j.ucl.2015.08.013
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Pichler Martin
- Co-Autor*innen der Med Uni Graz
- Krassnig Lisa
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- Abstract:
- Testicular cancer processes a unique and clear miRNA expression signature. This differentiates testicular cancer from most other cancer types, which are usually more ambiguous when assigning miRNA patterns. As such, testicular cancer may represent a unique cancer type in which miRNAs find their use as biomarkers for cancer diagnosis and prognosis, with a potential to surpass the current available markers usually with low sensitivity. In this review, we present literature findings on miRNAs associated with testicular cancer, and discuss their potential diagnostic and prognostic values, as well as their potential as indicators of drug response in patients with testicular cancer. Copyright © 2016 Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Biomarkers, Tumor - genetics
- Gene Expression Regulation, Neoplastic -
- Humans -
- Male -
- MicroRNAs - analysis
- Neoplasms, Germ Cell and Embryonal - genetics
- Prognosis -
- Sensitivity and Specificity -
- Testicular Neoplasms - genetics