Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Magaña, M; Massone, C; Magaña, P; Cerroni, L.
Clinicopathologic Features of Hydroa Vacciniforme-Like Lymphoma: A Series of 9 Patients.
Am J Dermatopathol. 2016; 38(1):20-25
Doi: 10.1097/DAD.0000000000000385
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Cerroni Lorenzo
- Co-authors Med Uni Graz
- Massone Cesare
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- Abstract:
- Hydroa vacciniforme-like lymphoma is a recently recognized cutaneous T-cell lymphoma associated with Epstein-Barr virus. The disease is observed in children of Latin American or Asian ethnicity. The authors report the clinical, histopathological, and immunophenotypical features of 9 new Mexican patients (M:F = 2:1; mean age, 14.5 years; median age, 13.3 years; age range, 4-27 years), expanding on previous observations of this elusive disease. The most common clinical aspects were persistent facial edema with necroses and pitted scars. Histopathological analyses revealed variably dense lymphoid infiltrates with common angiodestructive features. Neoplastic cells expressed CD3 and cytotoxic markers in all cases and were constantly positive for Epstein-Barr virus (EBER-1). Expression of other markers was variable. Follow-up data revealed that all patients died within 6 months or less, thus showing a very aggressive course with poor prognosis.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- CD3 Complex - analysis
- Child -
- Child, Preschool -
- Cicatrix - pathology
- Cicatrix - virology
- Edema - pathology
- Edema - virology
- Epstein-Barr Virus Infections - complications
- Extremities - pathology
- Face - pathology
- Facial Neoplasms - chemistry
- Facial Neoplasms - pathology
- Facial Neoplasms - virology
- Female -
- Humans -
- Hydroa Vacciniforme - pathology
- Hydroa Vacciniforme - virology
- Immunohistochemistry -
- Lymphoma, T-Cell, Cutaneous - chemistry
- Lymphoma, T-Cell, Cutaneous - pathology
- Lymphoma, T-Cell, Cutaneous - virology
- Male -
- Mexico -
- Necrosis - pathology
- Necrosis - virology
- Prognosis -
- Torso - pathology
- Young Adult -
- Find related publications in this database (Keywords)
- hydroa-like lymphoma
- hydroa vacciniforme-like cutaneous T-cell lymphoma
- angiocentric cutaneous T-cell lymphoma of childhood
- Epstein-Barr virus
- hydroa vacciniformis
- cutaneous T-cell lymphoma