Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Karremann, M; Hoffmann, M; Benesch, M; Kwiecien, R; von Bueren, AO; Kramm, CM.
Secondary Solid Malignancies After High-Grade Glioma Treatment in Pediatric Patients.
Pediatr Hematol Oncol. 2015; 32(7):467-473
Doi: 10.3109/08880018.2015.1050615
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Benesch Martin
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- Abstract:
- Due to the poor survival in high-grade glioma (HGG), secondary solid malignancies (SSM) following pediatric HGG are scarce. The authors present the experience from the HIT-HGG database in Germany, Austria, and Switzerland. Five out of 1228 pediatric HGG patients developed a SSM following a latency of 29-122 months from primary HGG diagnosis. In 4 patients, the SSM may be attributed to previous radiotherapy or a tumor predisposition syndrome, reflected by a markedly increased cumulative incidence rate of SSM in patients with tumor predisposition. Survival was devastating, since none of the patients survived beyond 18 months from SSM diagnosis.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Child -
- Child, Preschool -
- Databases, Factual -
- Disease-Free Survival -
- Female -
- Glioma - mortality
- Glioma - therapy
- Humans -
- Incidence -
- Infant -
- Infant, Newborn -
- Male -
- Neoplasms, Second Primary - mortality
- Neoplasms, Second Primary - therapy
- Survival Rate -
- Find related publications in this database (Keywords)
- children
- glioblastoma
- high-grade glioma
- secondary solid malignancies