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Neubauer, KM; Mader, JK; Höll, B; Aberer, F; Donsa, K; Augustin, T; Schaupp, L; Spat, S; Beck, P; Fruhwald, FM; Schnedl, C; Rosenkranz, AR; Lumenta, DB; Kamolz, LP; Plank, J; Pieber, TR.
Standardized Glycemic Management with a Computerized Workflow and Decision Support System for Hospitalized Patients with Type 2 Diabetes on Different Wards.
Diabetes Technol Ther. 2015; 17(10):685-692
Doi: 10.1089/dia.2015.0027
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- Führende Autor*innen der Med Uni Graz
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Lichtenegger Katharina
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Mader Julia
- Co-Autor*innen der Med Uni Graz
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Fruhwald Friedrich
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Höll Bernhard
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Kamolz Lars-Peter
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Lumenta David Benjamin
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Pieber Thomas
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Rosenkranz Alexander
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Schaupp Lukas
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Schnedl Christian
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- Abstract:
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This study investigated the efficacy, safety, and usability of standardized glycemic management by a computerized decision support system for non-critically ill hospitalized patients with type 2 diabetes on four different wards.
In this open, noncontrolled intervention study, glycemic management of 99 patients with type 2 diabetes (62% acute admissions; 41 females; age, 67±11 years; hemoglobin A1c, 65±21 mmol/mol; body mass index, 30.4±6.5 kg/m(2)) on clinical wards (Cardiology, Endocrinology, Nephrology, Plastic Surgery) of a tertiary-care hospital was guided by GlucoTab(®) (Joanneum Research GmbH [Graz, Austria] and Medical University of Graz [Graz, Austria]), a mobile decision support system providing automated workflow support and suggestions for insulin dosing to nurses and physicians.
Adherence to insulin dosing suggestions was high (96.5% bolus, 96.7% basal). The primary outcome measure, percentage of blood glucose (BG) measurements in the range of 70-140 mg/dL, occurred in 50.2±22.2% of all measurements. The overall mean BG level was 154±35 mg/dL. BG measurements in the ranges of 60-70 mg/dL, 40-60 mg/dL, and <40 mg/dL occurred in 1.4%, 0.5%, and 0.0% of all measurements, respectively. A regression analysis showed that acute admission to the Cardiology Ward (+30 mg/dL) and preexisting home insulin therapy (+26 mg/dL) had the strongest impact on mean BG. Acute admission to other wards had minor effects (+4 mg/dL). Ninety-one percent of the healthcare professionals felt confident with GlucoTab, and 89% believed in its practicality and 80% in its ability to prevent medication errors.
An efficacious, safe, and user-accepted implementation of GlucoTab was demonstrated. However, for optimized personalized patient care, further algorithm modifications are required.
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Aged -
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Algorithms -
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Austria -
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Blood Glucose - analysis
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Decision Support Systems, Clinical -
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Diabetes Mellitus, Type 2 - blood
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Diabetes Mellitus, Type 2 - drug therapy
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Drug Administration Schedule -
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Female -
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Glycated Hemoglobin A - analysis
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Humans -
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Hypoglycemic Agents - administration & dosage
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Hypoglycemic Agents - therapeutic use
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Inpatients -
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Insulin - administration & dosage
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Insulin - therapeutic use
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Male -
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Middle Aged -
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Software -
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Workflow -