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SHR Neuro Cancer Cardio Lipid Metab Microb
Schwaberger, B; Pichler, G; Binder-Heschl, C; Baik, N; Avian, A; Urlesberger, B.
Transitional Changes in Cerebral Blood Volume at Birth.
Neonatology. 2015; 108(4):253-258
Doi: 10.1159/000437347
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Schwaberger Bernhard
- Co-authors Med Uni Graz
- Avian Alexander
- Baik-Schneditz Nariae
- Binder-Heschl Corinna
- Pichler Gerhard
- Urlesberger Berndt
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- Abstract:
- Near-infrared spectroscopy (NIRS) enables non-invasive measurements of changes in the concentration of oxygenated (x0394;HbO2) and reduced (x0394;HbR) haemoglobin. Changes in total haemoglobin (x0394;HbT = x0394;HbO2 + x0394;HbR) provide information on changes in cerebral blood volume (CBV). The aim was to evaluate the behaviour of CBV during immediate postnatal transition in term infants. This observational study was conducted at the Medical University of Graz. NIRS measurements were carried out in term infants without need for respiratory support by using 'NIRO 200-NX' (Hamamatsu) over the first 15 min after birth. 109 infants with a mean gestational age of 38 + 6 weeks (±7 days) and birth weight of 3,242 g (±481) were included. Related to a reference value at minute 15, a significant decrease of HbT was observed for each minute within the study period. The mean (±SD) decrease of HbT of 17 (±40) µmol/l from minutes 2 to 15 represents a decrease of CBV of 1.0 ml/100 g brain (±2.2). In healthy newborns, CBV decreased over the whole study period. This likely reflects a physiological process. The impact and clinical relevance of different CBV behaviour during immediate transition needs to be investigated in further studies. © 2015 S. Karger AG, Basel.
- Find related publications in this database (using NLM MeSH Indexing)
- -
- Brain - blood supply
- Cerebrovascular Circulation - physiology
- Female -
- Gestational Age -
- Heart Rate -
- Humans -
- Infant, Newborn -
- Male -
- Oxygen - blood
- Oxyhemoglobins - metabolism
- Parturition -
- Spectroscopy, Near-Infrared -
- Find related publications in this database (Keywords)
- Cerebral blood volume
- Cerebral tissue oxygenation
- Neonatal transition
- Near-infrared spectroscopy