Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Lanz, S; Schwinger, W; Sovinz, P; Lackner, H; Resch, B; Urlesberger, B; Sipurzynski, S; Urban, C.
Successful Unrelated Stem Cell Transplantation in an Infant With Congenital Acute Myelogenous Leukemia FAB M5 Showing Massive Cutaneous Infiltrations--A Challenging Multidisciplinary Approach.
Pediatr Blood Cancer. 2016; 63(1):160-163
Doi: 10.1002/pbc.25703
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Lanz Sofia
- Co-Autor*innen der Med Uni Graz
- Lackner Herwig
- Resch Bernhard
- Ritter-Sovinz Petra
- Schwinger Wolfgang
- Sipurzynski Sabine
- Urban Ernst-Christian
- Urlesberger Berndt
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- Abstract:
- The multidisciplinary management of a male neonate presenting with congenital acute myelogenous leukemia of monoblastic phenotype is reported using conventional chemotherapy, high dose conditioning, and matched unrelated donor stem cell transplantation. These therapies were combined to add a graft versus leukemia effect to the treatment. Although chimerism studies showed a decrease of donor white blood cells, T-cells remained stable of allogeneic origin. We hypothesize that a continuous graft versus leukemia effect results in minimal residual disease negativity for now more than 18 months since stem cell transplantation. © 2015 Wiley Periodicals, Inc.
- Find related publications in this database (using NLM MeSH Indexing)
- Graft vs Leukemia Effect -
- Humans -
- Infant, Newborn -
- Leukemia, Myeloid, Acute - congenital
- Leukemia, Myeloid, Acute - pathology
- Leukemia, Myeloid, Acute - therapy
- Male -
- Patient Care Team -
- Stem Cell Transplantation -
- Find related publications in this database (Keywords)
- allogeneic stem cell transplantation
- congenital acute myelogenous leukemia
- infant