Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Porta, S; Stossier, H; Gell, H; Moser, M; Pamminger, N; Kisters, K.
Provoked metabolic- and Mg changes in CFS patients and in a healthy Mg substituted group - a quantitative survey
TRACE ELEM ELECTROLY. 2015; 32(3): 105-111.
Doi: 10.5414/TEX01375
Web of Science
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- Porta Sepp
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- Abstract:
- Out of 100 mu L of capillary blood of healthy. Mg-substituted probands, having been fatigued the previous week and of chronic fatigue syndrome (CFS) patients, blood glucose, lactate, pH, pCO(2), pO(2), ionized Mg, Ca, and K have been determined, base excess has been calculated as well as "residual acidity", an estimate of fatty acid concentration. Samples were collected from each group before and after a moderate physical workload. It turned out that in CFS patients (contrary to fatigued healthy persons) a moderate physical challenge led to lactate increase along with a fall in glucose, to unchanged, low Mg concentrations, mostly to a lack of pH overcompensation and a loss of blood O-2, even in those who were still able to overcompensate. Characteristically, in CFS patients lactate and residual acidity correlate positively (in contrast to controls), indicating high energy demand in the periphery. The same increased energy turnover causes a 30% higher Mg loss than in controls. Even without workload, the increased susceptibility. of CFS patients to metabolic overreaction can be quantified by Mg, glucose, and pH correlations. Mg concentrations seem to play a pivotal role in a possible amelioration of the illness.
- Find related publications in this database (Keywords)
- chronic fatigue syndrome (CFS)
- quantification
- Mg dynamics
- workload
- metabolism