Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sitić, S; Mirt-Dabić, M; Brcić, L; Juros, Z; Hutinec, Z; Kruslin, B.
DNA ploidy in thymoma and associated multiple primary malignancies in the same patient.
Acta Clin Croat. 2008; 47(3):155-159
(- Case Report)
[OPEN ACCESS]
Web of Science
PubMed
- Co-Autor*innen der Med Uni Graz
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- Abstract:
- Thymoma is an uncommon neoplasm derived from thymic epithelium. It is located in the anterosuperior mediastinum. Thymoma may be associated with different types of additional primary malignancies; however, colorectal adenocarcinoma and thyroid cancer appear to be most common. A case is presented of a 63-year-old woman with type A thymoma and two other primary carcinomas of the breast and colon that were previously diagnosed. The patient underwent surgery due to metastatic colon cancer of the lung and yet another primary tumor was found in the mediastinum, later diagnosed as thymoma. A normal diploid pattern was found in the samples of thymoma and colon carcinoma, whereas those of breast carcinoma and metastatic tumor of the lung showed aneuploidy. On the basis of previous studies and our case, it is concluded that the occurrence of extrathymic malignancies does not correlate with the biologic behavior and DNA ploidy of thymoma.
- Find related publications in this database (using NLM MeSH Indexing)
- Breast Neoplasms - genetics Breast Neoplasms - pathology
- Colonic Neoplasms - genetics Colonic Neoplasms - pathology Colonic Neoplasms - secondary
- DNA, Neoplasm - genetics
- Female -
- Humans -
- Lung Neoplasms - genetics Lung Neoplasms - pathology
- Middle Aged -
- Neoplasms, Multiple Primary - genetics
- Ploidies -
- Thymoma - genetics Thymoma - pathology
- Thymus Neoplasms - genetics Thymus Neoplasms - pathology
- Find related publications in this database (Keywords)
- Thymus neoplasms, diagnosis
- Thymoma, diagnosis
- Thymoma, pathology
- DNA neoplasms, analysis
- Case report