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Brcić, I; Brcić, L; Kuzmanić, D; Corić, M; Corić, M.
Fibronectin glomerulopathy in a 34-year-old man: a case report.
Ultrastruct Pathol. 2010; 34(4): 240-242.
Doi: 10.3109/01913121003783209
(- Case Report)
Web of Science
PubMed
FullText
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- Leading authors Med Uni Graz
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Brcic Iva
- Co-authors Med Uni Graz
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Brcic Luka
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- Abstract:
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Fibronectin glomerulopathy is an inherited non-immune-mediated glomerulopathy associated with the massive deposition of fibronectin. It presents with proteinuria, microscopic hematuria, and hypertension that lead to end-stage renal failure in the second to sixth decade of life. A 34-year-old male was referred with proteinuria (6 g/day), microscopic hematuria and hypertension (220/130 mmHg). Renal biopsy specimen showed massive deposits of fibronectin in the mesangium and subendothelial spaces. After 20 months of multidrug treatment his renal function is stable.
- Find related publications in this database (using NLM MeSH Indexing)
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Adult -
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Fibronectins - metabolism
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Glomerular Mesangium - metabolism Glomerular Mesangium - ultrastructure
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Hematuria - drug therapy Hematuria - genetics Hematuria - pathology
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Humans -
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Hypertension - drug therapy Hypertension - genetics Hypertension - pathology
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Kidney Diseases - drug therapy Kidney Diseases - genetics Kidney Diseases - metabolism Kidney Diseases - pathology
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Kidney Glomerulus - metabolism Kidney Glomerulus - pathology
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Male -
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Microscopy, Electron, Transmission -
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Proteinuria - drug therapy Proteinuria - genetics Proteinuria - pathology
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Treatment Outcome -
- Find related publications in this database (Keywords)
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electron microscopy
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fibronectin
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glomerulopathy
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immunofluorescence
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proteinuria