Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Benesch, M; Lackner, H; Pilhatsch, A; Gürtl-Lackner, B; Schwinger, W; Urban, C.
Long-term Remission in a Female With Multiple Relapsed Juvenile Granulosa Cell Tumor.
J Pediatr Hematol Oncol. 2015; 37(8):e486-e489
Doi: 10.1097/MPH.0000000000000387
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Benesch Martin
- Co-authors Med Uni Graz
- Gürtl-Lackner Barbara
- Lackner Herwig
- Schwinger Wolfgang
- Urban Ernst-Christian
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- Abstract:
- A 4 ½-year-old female was diagnosed with ovarian juvenile granulosa cell tumor stage IA. After complete tumor resection she received 4 courses of chemotherapy due to unfavorable histopathologic features (high mitotic index, high microvessel density, blood vessel invasion). One year after diagnosis, she experienced paraaortic lymph node relapse treated with surgery, local radiotherapy, and conventional and high-dose chemotherapy. A second, paratracheal lymph node relapse 7 months later necessitated surgical removal and radiotherapy. Subsequently an adjuvant antiangiogenesis-based treatment including paclitaxel, bevacizumab, thalidomide, and pegylated interferon was initiated and continued for 2 years. The female is now in third complete remission 6 years after second relapse.
- Find related publications in this database (using NLM MeSH Indexing)
- Antineoplastic Combined Chemotherapy Protocols - therapeutic use
- Child, Preschool -
- Female -
- Granulosa Cell Tumor - secondary
- Granulosa Cell Tumor - therapy
- Humans -
- Lymph Node Excision -
- Lymphatic Irradiation -
- Lymphatic Metastasis - radiotherapy
- Neoplasm Staging -
- Neovascularization, Pathologic - drug therapy
- Ovarian Neoplasms - drug therapy
- Ovarian Neoplasms - pathology
- Ovarian Neoplasms - surgery
- Ovariectomy -
- Remission Induction -
- Salvage Therapy -
- Find related publications in this database (Keywords)
- juvenile granulosa cell tumor
- children
- relapse
- treatment
- antiangiogenesis