Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Porta, S; Himly, C; Rinner, I; Schwarz, U; Werner, M; Poncza, B; Korsatko, W.
Isoprenaline cannot act on pancreatic beta cells without hyperglycemia or alpha-block.
EXP PATHOL. 1991; 43(1-2): 57-61.
Doi: 10.1016/S0232-1513(11)80144-1
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- Führende Autor*innen der Med Uni Graz
- Porta Sepp
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- Abstract:
- During long-term increase in isoprenaline (pronounced beta-effect) and isoprenaline plus regitine (pure beta-effect) pancreatic insulin-secretion still depended mostly on blood glucose levels. This means that increased beta-effect during normo- or hypoglycemia could not cause a higher insulin-secretion. Only during additional alpha-receptor blockade insulin-secretion was slightly but insufficiently increased. Catecholamines seem to be more regulator than originator of the insulin secretory process.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Blood Glucose - metabolism
- Epinephrine - blood
- Insulin - blood
- Islets of Langerhans - drug effects
- Isoproterenol - blood
- Male - blood
- Norepinephrine - blood
- Pancreas - metabolism
- Phentolamine - blood
- Rats - blood
- Rats, Inbred Strains - blood
- Receptors, Adrenergic, alpha - drug effects
- Find related publications in this database (Keywords)
- Isoprenaline
- Pancreatic Beta-Cells
- Hyperglycemia
- Alpha-Receptor Blockade
- Regitine
- Insulin Secretion
- Receptor Blockade
- Alpha
- Catecholamines
- Beta-Cells
- Pancreatic
- Hypoglycemia
- Glucose
- Blood
- Blood Glucose