Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Glatz, M; Resinger, A; Semmelweis, K; Ambros-Rudolph, CM; Müllegger, RR.
Clinical spectrum of skin manifestations of Lyme borreliosis in 204 children in Austria.
Acta Derm Venereol. 2015; 95(5):565-571
Doi: 10.2340/00015555-2000
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- Führende Autor*innen der Med Uni Graz
- Glatz Martin
- Co-Autor*innen der Med Uni Graz
- Ambros-Rudolph Christina
- Muellegger Robert
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- Abstract:
- The spectrum of skin manifestations of Lyme borreliosis in children is not well characterized. We conducted a retrospective study to analyze the clinical characteristics, seroreactivity to Borrelia burgdorferi sensu lato, and outcome after treatment in 204 children with skin manifestations of Lyme borreliosis seen in 1996-2011. Solitary erythema migrans was the most common manifestation (44.6%), followed by erythema migrans with multiple lesions (27%), borrelial lymphocytoma (21.6%), and acrodermatitis chronica atrophicans (0.9%). A collision lesion of a primary borrelial lymphocytoma and a surrounding secondary erythema migrans was diagnosed in 5.9% of children. Rate of seroreactivity to B. burgdorferi s.l. was lower in solitary erythema migrans compared to other diagnosis groups. Amoxicillin or phenoxymethylpenicillin led to complete resolution of erythema migrans within a median of 6 (solitary) and 14 days (multiple lesions), respectively, and of borrelia lymphocytoma within a median of 56 days. In conclusion, erythema migrans with multiple lesions and borrelial lymphocytoma appear to be more frequent in children than in adults, whereas acrodermatitis chronica atrophicans is a rarity in childhood. The outcome after antibiotic therapy was excellent in children, and appears to be better than in adults.
- Find related publications in this database (using NLM MeSH Indexing)
- Acrodermatitis - drug therapy
- Acrodermatitis - etiology
- Acrodermatitis - physiopathology
- Administration, Oral -
- Adolescent -
- Anti-Bacterial Agents - administration & dosage
- Borrelia burgdorferi - isolation & purification
- Child -
- Child, Preschool -
- Cohort Studies -
- Drug Therapy, Combination -
- Erythema Chronicum Migrans - drug therapy
- Erythema Chronicum Migrans - etiology
- Erythema Chronicum Migrans - physiopathology
- Female -
- Follow-Up Studies -
- Humans -
- Injections, Intravenous -
- Lyme Disease - complications
- Lyme Disease - diagnosis
- Lyme Disease - drug therapy
- Male -
- Pseudolymphoma - drug therapy
- Pseudolymphoma - etiology
- Pseudolymphoma - physiopathology
- Retrospective Studies -
- Risk Assessment -
- Severity of Illness Index -
- Treatment Outcome -
- Find related publications in this database (Keywords)
- pediatric Lyme borreliosis
- erythema migrans
- borrelial lymphocytoma
- acrodermatitis chronica atrophicans