Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Adjedj, J; Toth, GG; De Bruyne, B.
Invasive measures of myocardial perfusion and ischemia.
Prog Cardiovasc Dis. 2015; 57(6):555-565
Doi: 10.1016/j.pcad.2015.03.002
Web of Science
PubMed
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FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Toth-Gayor Gabor
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- Abstract:
- Until recently, our understanding of coronary artery disease (CAD) has been largely based on a purely anatomical approach as derived from the invasive angiogram. The confirmation of the diagnosis of "significant" CAD, the assessment of its extent, the risk stratification of patients, the therapeutic decisions, the definition of study end-points, and the validation of non-invasive testing, all mainly relied on "eyeballing" the angiogram, i.e. a subjective evaluation of the presence of at least 50% (or 70%) diameter stenosis.With the development of invasive, wire-based, means to quantify coronary pressure and flow with high spatial resolution, one realized that purely angiographic metrics correlated poorly with functional information. Currently, it is admitted that both anatomical and functional information are needed to define CAD and to optimize its management. In the present review, we summarize the main characteristics of invasive functional indices of ischemia and perfusion. Copyright © 2015 Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Blood Flow Velocity -
- Blood Pressure -
- Cardiac Catheterization -
- Coronary Angiography -
- Fractional Flow Reserve, Myocardial -
- Hemodynamics -
- Humans -
- Microcirculation -
- Models, Cardiovascular -
- Myocardial Ischemia - diagnostic imaging
- Myocardial Ischemia - physiopathology
- Myocardial Perfusion Imaging - methods
- Predictive Value of Tests -
- Prognosis -
- Thermodilution -
- Vascular Resistance -
- Find related publications in this database (Keywords)
- Coronary angiogram
- Coronary artery disease
- Microcirculation
- Coronary flow reserve
- Fractional flow reserve
- Ischemic testing
- Index of microvascular resistance