Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Tibrewal, S; Malagelada, F; Jeyaseelan, L; Posch, F; Scott, G.
Single-stage revision for the infected total knee replacement: results from a single centre.
Bone Joint J. 2014; 96-B(6): 759-764.
Doi: 10.1302/0301-620X.96B6.33086
Web of Science
PubMed
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FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Posch Florian
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- Abstract:
- Peri-prosthetic infection is amongst the most common causes of failure following total knee replacement (TKR). In the presence of established infection, thorough joint debridement and removal of all components is necessary following which new components may be implanted. This can be performed in one or two stages; two-stage revision with placement of an interim antibiotic-loaded spacer is regarded by many to be the standard procedure for eradication of peri-prosthetic joint infection. We present our experience of a consecutive series of 50 single-stage revision TKRs for established deep infection performed between 1979 and 2010. There were 33 women and 17 men with a mean age at revision of 66.8 years (42 to 84) and a mean follow-up of 10.5 years (2 to 24). The mean time between the primary TKR and the revision procedure was 2.05 years (1 to 8). Only one patient required a further revision for recurrent infection, representing a success rate of 98%. Nine patients required further revision for aseptic loosening, according to microbiological testing of biopsies taken at the subsequent surgery. Three other patients developed a further septic episode but none required another revision. These results suggest that a single-stage revision can produce comparable results to a two-stage revision. Single-stage revision offers a reduction in costs as well as less morbidity and inconvenience for patients. ©2014 The British Editorial Society of Bone & Joint Surgery.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Antibiotic Prophylaxis - methods
- Arthroplasty, Replacement, Knee - adverse effects Arthroplasty, Replacement, Knee - methods
- Cohort Studies -
- Confidence Intervals -
- Debridement - methods
- Device Removal - methods
- Female -
- Follow-Up Studies -
- Humans -
- Kaplan-Meier Estimate -
- Knee Prosthesis -
- Male -
- Middle Aged -
- Osteoarthritis, Knee - radiography Osteoarthritis, Knee - surgery
- Prosthesis Design -
- Prosthesis Failure -
- Prosthesis-Related Infections - drug therapy Prosthesis-Related Infections - radiography Prosthesis-Related Infections - surgery
- Reoperation - methods
- Retrospective Studies -
- Risk Assessment -
- Treatment Outcome -