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Eibisberger, M; Resch, E; Resch, B.
Surfactant replacement therapy in extremely low gestational age newborns.
Indian Pediatr. 2015; 52(3):227-230 Doi: 10.1007/s13312-015-0612-3 [OPEN ACCESS]
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Führende Autor*innen der Med Uni Graz
Eibisberger Monika
Resch Bernhard
Co-Autor*innen der Med Uni Graz
Resch-Poteralski Elisabeth
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Abstract:
There is a growing body of evidence over the last years suggesting continuous positive airway pressure (CPAP) ventilation being the first choice of ventilatory support in newborns with extremely low gestational age, and early rescue surfactant treatment being as effective as prophylactic therapy. The Intubation Surfactant Extubation procedure is discussed as an alternative procedure that may have the potential to combine the positive effects of surfactant and early CPAP. A further mode of surfactant administration, administration via a thin endotracheal catheter during spontaneous breathing with CPAP, has recently come into clinical use. This less invasive surfactant administration technique shows some short-term benefits but still cannot be recommended for general use in this vulnerable population. Long-term follow-up studies are needed to allow new recommendations on surfactant therapy in this high-risk population.
Find related publications in this database (using NLM MeSH Indexing)
Continuous Positive Airway Pressure - methods
Humans -
Infant, Extremely Premature - physiology
Infant, Newborn -
Pulmonary Surfactants - therapeutic use
Respiratory Distress Syndrome, Newborn - drug therapy
Respiratory Distress Syndrome, Newborn - prevention & control

Find related publications in this database (Keywords)
Low birth weight
Prematurity
Respiratory distress syndrome
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