Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Erovic, BM; Schopper, C; Pammer, J; Vormittag, L; Maleki, A; Brunner, M; Heiduschka, G; Grasl, MCh; Thurnher, D.
Multimodal treatment of patients with minor salivary gland cancer in the case of recurrent disease.
Head Neck. 2010; 32(9):1167-1172
Doi: 10.1002/hed.21312
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Thurnher Dietmar
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- Abstract:
- Our aim in this study was to identify prognostic factors and the optimal therapeutic management in patients with minor salivary gland carcinomas. Overall and disease-free survival and overall survival after recurrence in patients with adenoidcystic carcinoma (n = 25), mucoepidermoid carcinoma (n = 8), adenocarcinoma (n = 5), carcinoma ex pleomorphic adenoma (n = 4), and others (n = 5) were correlated to clinical data. Overall survival correlated to treatment modality (p = .039) and T classification (p = .003), whereas prolonged disease-free interval correlated to treatment (p < .001) and T classification (p = .009). Overall survival after recurrence correlated to treatment of recurrence (p = .006) and initial T classification (p = .02). Multivariate analysis showed that overall survival after recurrence correlated to treatment of recurrence (p = .019) and initial T classification (p = 0.019). T classification was a prognostic factor for overall survival (p = .002) and disease-free interval (p = .002). The initial tumor classification is a clinical predictor for patients' overall and disease-free survival and overall survival after recurrence. Multimodal treatment significantly improves patients' overall survival.
- Find related publications in this database (using NLM MeSH Indexing)
- Adenoma, Pleomorphic - mortality
- Adenoma, Pleomorphic - pathology
- Adenoma, Pleomorphic - therapy
- Adult -
- Aged -
- Aged, 80 and over -
- Analysis of Variance -
- Carcinoma, Adenoid Cystic - mortality
- Carcinoma, Adenoid Cystic - pathology
- Carcinoma, Adenoid Cystic - therapy
- Carcinoma, Mucoepidermoid - mortality
- Carcinoma, Mucoepidermoid - pathology
- Carcinoma, Mucoepidermoid - therapy
- Chemotherapy, Adjuvant -
- Cohort Studies -
- Combined Modality Therapy -
- Disease-Free Survival -
- Female -
- Follow-Up Studies -
- Humans -
- Kaplan-Meier Estimate -
- Male -
- Middle Aged -
- Multivariate Analysis -
- Neoplasm Recurrence, Local - mortality
- Neoplasm Recurrence, Local - pathology
- Neoplasm Recurrence, Local - therapy
- Neoplasm Staging -
- Proportional Hazards Models -
- Radiotherapy, Adjuvant -
- Retrospective Studies -
- Salivary Gland Neoplasms - mortality
- Salivary Gland Neoplasms - pathology
- Salivary Gland Neoplasms - therapy
- Salivary Glands, Minor - pathology
- Salivary Glands, Minor - surgery
- Survival Analysis -
- Treatment Outcome -
- Find related publications in this database (Keywords)
- salivary gland tumors
- recurrence
- treatment modalities