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Gewählte Publikation:

Locker, GJ; Wagner, A; Peter, A; Staudinger, T; Marosi, C; Rintelen, C; Knapp, S; Malzer, R; Weiss, K; Metnitz, P.
Lethal Waterhouse-Friderichsen syndrome in posttraumatic asplenia.
J Trauma. 1995; 39(4):784-786 Doi: 10.1097/00005373-199510000-00035 (- Case Report)
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Co-Autor*innen der Med Uni Graz
Metnitz Philipp
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Abstract:
We herein report a case of fulminant lethal Waterhouse-Friderichsen syndrome in an elderly female patient seven years after posttraumatic splenectomy. In contrast to various reports, this patient had not been vaccinated against Streptococcus pneumoniae, Neisseria meningitidis, or Haemophilus influenzae, respectively, although infections with these microorganisms are known to cause the main lethal diseases in asplenic patients. Again, we recommend obligatory vaccinations against the mentioned bacteria for it is known that this decreases the risk of fatal septic events in these patients. To optimize prevention, it is imperative to vaccinate patients undergoing splenectomy before discharge from hospital.
Find related publications in this database (using NLM MeSH Indexing)
Blood Coagulation Tests -
Fatal Outcome -
Female -
Hemodynamics - physiology
Humans -
Middle Aged -
Spleen - injuries
Splenectomy - adverse effects
Vaccination -
Waterhouse-Friderichsen Syndrome - blood
Waterhouse-Friderichsen Syndrome - etiology
Waterhouse-Friderichsen Syndrome - physiopathology

Find related publications in this database (Keywords)
WATERHOUSE-FRIDERICHSEN SYNDROME
OVERWHELMING POSTSPLENECTOMY INFECTION (OPSI)
PREVENTION
PNEUMOCOCCAL VACCINATION
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