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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Pietribiasi, M; Katzarski, K; Galach, M; Stachowska-Piętka, J; Schneditz, D; Lindholm, B; Waniewski, J.
Kinetics of plasma refilling during hemodialysis sessions with different initial fluid status.
ASAIO J. 2015; 61(3):350-356
Doi: 10.1097/MAT.0000000000000206
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- Co-authors Med Uni Graz
- Schneditz Daniel
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- Abstract:
- Removal of fluid excess from the plasma volume by ultrafiltration during hemodialysis (HD) is balanced by plasma refilling from the interstitium, driven mainly by the increase in plasma oncotic pressure. We calculated the plasma refilling coefficient (Kr, a parameter expressing the ratio of refilling rate to the increase in oncotic pressure) for nine patients, each undergoing two HD sessions differing by pretreatment fluid status and session time (shorter session, SH, 3.5 h, and longer session, LH, 4.5h). Relative blood volume change was measured online, and solute concentrations were measured regularly during the sessions. The volume of body compartments was measured by bioimpedance. The patients were more volume expanded before LH session (higher initial body mass and total body water). Oncotic pressure was similar for both sessions. The refilling rate, despite higher fluid overload in the LH sessions, was similar for both sessions. The final Kr values stabilized on similar levels (SH: 136.6 ± 55.6 ml/mm Hg/h and LH: 150.7 ± 73.6 ml/mm Hg/h) at similar times, notwithstanding the difference in initial fluid overload between the two groups, suggesting that Kr at dry weight is relatively insensitive to the initial fluid status of the patient.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Blood Volume - physiology
- Female -
- Hemodiafiltration -
- Humans -
- Kinetics -
- Male -
- Middle Aged -
- Ultrafiltration -
- Find related publications in this database (Keywords)
- hypotension
- ultrafiltration
- blood pressure
- extracellular volume
- blood volume
- plasma oncotic pressure