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Reisinger, EC; Wendelin, I; Gasser, R.
In vitro activity of trimethoprim against Borrelia burgdorferi.
Eur J Clin Microbiol Infect Dis. 1997; 16(6):458-460 Doi: 10.1007/BF02471911
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Co-authors Med Uni Graz: Gasser Robert; Wendelin Ilse
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Abstract:: A new culture medium has been developed to evaluate the activity of trimethoprim and sulfamethoxazole against Borrelia burgdorferi in vitro. In this specially modified Barbour-Stoenner-Kelly medium, in which antagonizing substances were reduced to a minimum, trimethoprim was more active against Borrelia burgdorferi than against a sensitive strain of Escherichia coli, but sulfamethoxazole was not active against Borrelia burgdorferi.
Find related publications in this database (using NLM MeSH Indexing): Anti-Bacterial Agents -; Anti-Infective Agents, Urinary - pharmacology; Borrelia burgdorferi Group - drug effects; Colony Count, Microbial - drug effects; Culture Media - chemistry; Drug Evaluation, Preclinical - chemistry; Drug Therapy, Combination - pharmacology; Escherichia coli - drug effects; Microbial Sensitivity Tests - drug effects; Sulfamethoxazole - pharmacology; Trimethoprim - pharmacology