Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Stift, J; Baba, HA; Huber, E; Federmann, B; Fischer, HP; Schmitt-Graeff, A; Baurmann, H; Bethge, W; Schirmacher, P; Wrba, F; Greinix, H; Fend, F; Schwerdtfeger, R; Shulman, HM; Wolff, D; Longerich, T; Liver Pathology Group of the German-Austrian-Swiss Working Group on GvHD.
Consensus on the histopathological evaluation of liver biopsies from patients following allogeneic hematopoietic cell transplantation.
Virchows Arch. 2014; 464(2): 175-190.
Doi: 10.1007/s00428-013-1528-8
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Greinix Hildegard
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- Abstract:
- After allogeneic hematopoietic cell transplantation (alloHCT) liver biopsy is performed for enigmatic liver disorders when noninvasive diagnostic steps have failed in establishing a definitive diagnosis. This document provides an updated consensus on the prerequisites for proper evaluation of liver biopsies in alloHCT patients and the histological diagnostic criteria for liver graft-versus-host disease (GvHD). The Working Group's recommendations for the histological diagnosis of liver GvHD were derived from the peer-reviewed literature and from the consensus diagnosis of a total of 30 coded liver biopsies. Acceptance of the recommendations was tested by a survey distributed to all HCT centers in Austria, Germany and Switzerland. Consensus was achieved for biopsy indications, methods of sample acquisition and processing, reporting and interpretation of biopsy findings. As GvHD is variably treated and the treatment modalities have changed over time, the panel endorses the use of more frequent biopsies in clinical studies in order to improve the present challenging clinical and diagnostic situation.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Biopsy -
- Child -
- Child, Preschool -
- Female -
- Graft vs Host Disease - diagnosis
- Hematopoietic Stem Cell Transplantation - adverse effects
- Humans -
- Liver - pathology
- Male -
- Middle Aged -
- Transplantation, Homologous -
- Young Adult -
- Find related publications in this database (Keywords)
- Liver
- GvHD
- Biopsy
- Consensus