Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Staufer, K; Halilbasic, E; Trauner, M; Kazemi-Shirazi, L.
Cystic fibrosis related liver disease--another black box in hepatology.
Int J Mol Sci. 2014; 15(8):13529-13549
Doi: 10.3390/ijms150813529
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Co-authors Med Uni Graz
- Halilbasic Emina
- Trauner Michael
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Due to improved medical care, life expectancy in patients with cystic fibrosis (CF) has veritably improved over the last decades. Importantly, cystic fibrosis related liver disease (CFLD) has become one of the leading causes of morbidity and mortality in CF patients. However, CFLD might be largely underdiagnosed and diagnostic criteria need to be refined. The underlying pathomechanisms are largely unknown, and treatment strategies with proven efficacy are lacking. This review focuses on current invasive and non-invasive diagnostic standards, the current knowledge on the pathophysiology of CFLD, treatment strategies, and possible future developments.
- Find related publications in this database (using NLM MeSH Indexing)
- Biomarkers - blood
- Carrier Proteins - metabolism
- Cholangitis, Sclerosing - diagnosis
- Cystic Fibrosis - complications
- Diagnosis, Differential -
- Humans -
- Liver Diseases - diagnosis
- Liver Transplantation -
- Membrane Glycoproteins - metabolism
- Non-alcoholic Fatty Liver Disease - diagnosis
- Find related publications in this database (Keywords)
- cystic fibrosis
- bile acid transporters
- gut liver axis
- non-invasive diagnostics
- cholestasis