Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Rabitsch, W; Brugger, SA; Trubel, W; Keil, F; Greinix, HT; Kalhs, P.
Streptococcus pneumoniae mycotic aortic aneurysm after allogeneic bone marrow transplantation.
Transplantation. 2002; 74(7):1048-1050
Doi: 10.1097/01.TP.0000026308.30476.C0
(- Case Report)
Web of Science
PubMed
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FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Greinix Hildegard
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- Abstract:
- Streptococcus pneumoniae (SP) is a common cause of community-acquired pneumonia and accounts for up to 30% of all cases of pneumonia. Patients with chronic graft-versus-host-disease (GvHD) after allogeneic bone marrow transplantation (BMT) have a high susceptibility to SP infections. So far, mycotic aneurysm resulting from SP has not been reported after BMT. We report on a patient with extensive, chronic GvHD who developed low back pain 22 months after allogeneic BMT. Computed tomography of the abdomen displayed mycotic, saccular aneurysmatic enlargement of the infrarenal aorta, with leakage of contrast medium into the aneurysm. The aneurysm was resected, and the defect was closed with an autologous patch from the internal iliac artery. Bacteriologic samples from the abscess grew SP. The patient recovered uneventfully. This observation confirms the importance of pneumococcal prophylaxis after BMT and suggests that an aggressive diagnostic approach should always be considered in patients with chronic GvHD, even if they present with nonspecific symptoms.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aneurysm, Infected - complications Aneurysm, Infected - etiology Aneurysm, Infected - radiography Aneurysm, Infected - surgery
- Aortic Aneurysm - complications Aortic Aneurysm - etiology Aortic Aneurysm - radiography Aortic Aneurysm - surgery
- Bone Marrow Transplantation - adverse effects
- Chronic Disease -
- Female -
- Graft vs Host Disease - complications
- Humans -
- Pneumococcal Infections - complications Pneumococcal Infections - etiology Pneumococcal Infections - radiography Pneumococcal Infections - surgery
- Tomography, X-Ray Computed -
- Transplantation, Homologous -