Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Rabitsch, W; Staudinger, T; Locker, GJ; Köstler, WJ; Laczika, K; Frass, M; Knoebl, P; Greinix, HT; Kalhs, P; Keil, F.
Respiratory failure after stem cell transplantation: improved outcome with non-invasive ventilation.
Leuk Lymphoma. 2005; 46(8): 1151-1157.
Doi: 10.1080/10428190500097649
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Greinix Hildegard
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- Abstract:
- We retrospectively analyzed the efficacy of non-invasive ventilation in 35 patients with acute hypoxemic respiratory failure after autologous or allogeneic stem cell transplantation (SCT). Non-invasive ventilation was delivered by a standard face mask or helmet. Decisions to intubate were made according to standard criteria. Between 1993 and 2003, 836 patients underwent an autologous or allogeneic bone marrow or SCT. Eighty-two patients developed respiratory failure. Of these, 47 patients were initially intubated and mechanically ventilated. None of these patients survived. Thirty-five patients initially underwent non-invasive ventilation at the bone marrow transplant unit. Seven of these patients survived and were discharged from the hospital (20%). Eleven of the 35 (31%) patients improved within the first 4 h of non-invasive ventilation with respect to oxygenation and were regarded as responders. Seven of these patients survived to hospital discharge (64%), while all non-responders died (P<0.001). In all survivors, the partial pressure of arterial oxygen (PaO2) improved after the initiation of non-invasive ventilation. In non-survivors, PaO2 improved in only 4 of 28 patients (17%) (P<0.0001). Non-invasive ventilation in patients with acute respiratory failure after SCT could improve prognosis in a carefully selected group of patients.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Female -
- Hematologic Neoplasms - diagnosis Hematologic Neoplasms - therapy
- Humans -
- Male -
- Middle Aged -
- Oxygen - blood
- Prognosis -
- Respiratory Function Tests -
- Respiratory Insufficiency - etiology Respiratory Insufficiency - therapy
- Retrospective Studies -
- Stem Cell Transplantation - adverse effects
- Survival Analysis -
- Treatment Outcome -
- Find related publications in this database (Keywords)
- non-invasive ventilation
- stem cell transplantation
- acute respiratory failure