Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schulenburg, A; Kalhs, P; Oberhuber, G; Reiter, E; Base, W; Greinix, HT.
Gastrointestinal perforation early after peripheral blood stem cell transplantation for AL amyloidosis.
Bone Marrow Transplant. 1998; 22(3):293-295
Doi: 10.1038/sj.bmt.1701330
(- Case Report)
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- Co-Autor*innen der Med Uni Graz
- Greinix Hildegard
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- Abstract:
- The morbidity and mortality of AL amyloidosis is caused by the deposition of Ig light chains as amyloid protein in vital organs. With conventional therapy median survival of patients with AL amyloidosis is 10-14 months. With high-dose chemotherapy clinical remissions of organ-specific disease have been reported. Here, we present a patient with high-risk AL amyloidosis who was given high-dose therapy and a peripheral blood stem cell transplant. Four days later she died of gastrointestinal perforation due to amyloid infiltrations.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Amyloidosis - immunology Amyloidosis - pathology Amyloidosis - therapy
- Fatal Outcome -
- Female -
- Hematopoietic Stem Cell Transplantation - adverse effects
- Humans -
- Immunoglobulin lambda-Chains - metabolism
- Intestinal Perforation - etiology Intestinal Perforation - immunology Intestinal Perforation - pathology
- Transplantation, Autologous -
- Find related publications in this database (Keywords)
- AL amyloidosis
- blood stem cell transplantation
- gastrointestinal perforation