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SHR Neuro Cancer Cardio Lipid Metab Microb
Norooz, F; Urlesberger, B; Giordano, V; Klebermasz-Schrehof, K; Weninger, M; Berger, A; Olischar, M.
Decompressing posthaemorrhagic ventricular dilatation significantly improves regional cerebral oxygen saturation in preterm infants.
Acta Paediatr. 2015; 104(7):663-669
Doi: 10.1111/apa.12942
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Urlesberger Berndt
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- Abstract:
- This study aimed to delineate the impact of posthaemorrhagic ventricular dilatation (PHVD) on regional cerebral oxygen saturation (rcSO2) in preterm infants before and after ventricular decompression using near-infrared spectroscopy (NIRS). rcSO2 values were recorded, fractional tissue oxygen extraction (FTOE) was calculated, cerebral ultrasound scans were performed, and resistive indices and ventricular width were collected before and after decompression. Where possible, amplitude-integrated electroencephalography (aEEG) and visual evoked potentials (VEPs) were recorded before and after decompression. We included nine preterm infants: nine with cranial ultrasound scan data, eight with NIRS data, seven with aEEG data and four with VEPs. The resistive index was stable and remained unchanged after decompression in all patients. Before decompression, the mean rcSO2 value was 42.6 ± 12.9% and increased to 55 ± 12.2% after decompression. With increasing ventricular width, FTOE showed a mean value of 0.51 ± 0.05 and decreased to a mean of 0.39 ± 0.12 after decompression. Amplitude-integrated electroencephalography showed a more continuous pattern, and VEPs showed delayed latencies in all patients before intervention, improving afterwards. Near-infrared spectroscopy may be of additional clinical value in progressive PHVD to determine the optimal time point for ventricular decompression. ©2015 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
- Find related publications in this database (using NLM MeSH Indexing)
- Cerebral Ventricles - pathology
- Cerebrospinal Fluid Shunts -
- Cerebrovascular Circulation - physiology
- Dilatation, Pathologic -
- Electroencephalography -
- Evoked Potentials, Visual -
- Female -
- Humans -
- Hydrocephalus - etiology
- Hydrocephalus - metabolism
- Hydrocephalus - therapy
- Infant, Newborn -
- Infant, Premature -
- Infant, Premature, Diseases - metabolism
- Infant, Premature, Diseases - therapy
- Intracranial Hemorrhages - complications
- Intracranial Hemorrhages - metabolism
- Intracranial Hemorrhages - therapy
- Male -
- Oxygen Consumption - physiology
- Prospective Studies -
- Spectroscopy, Near-Infrared -
- Find related publications in this database (Keywords)
- Amplitude-integrated electroencephalography
- Hydrocephalus
- Near-infrared spectroscopy
- Posthaemorrhagic ventricular dilatation
- Visual evoked potentials