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SHR Neuro Cancer Cardio Lipid Metab Microb

Massone, C; Cerroni, L.
The many clinico-pathologic faces of actinic keratosis: an atlas.
Curr Probl Dermatol. 2015; 46(6):64-69 Doi: 10.1159/000366538
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Leading authors Med Uni Graz
Massone Cesare
Co-authors Med Uni Graz
Cerroni Lorenzo
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Abstract:
Actinic keratoses (AKs) are intraepithelial neoplasms formed by atypical keratinocyte proliferation. Histopathologically, typical AKs are characterized by a slightly thickened epidermis, usually with irregular downward buds, orthokeratosis alternating with parakeratosis ('pink and blue') with loss of the underlying granular layer and a disarrangement of the epidermis with atypical keratinocytes at the basal layer. There are several histopathological variants of AK according to the different degrees of keratinocytic atypia, epidermal hyperplasia/atrophy, inflammation and pigmentation. Some authors consider AK an early in situ squamous cell carcinoma and propose a classification of AK based on the extent of atypical keratinocytes in the epidermis. © 2015 S. Karger AG, Basel.
Find related publications in this database (using NLM MeSH Indexing)
Carcinoma, Squamous Cell - classification
Carcinoma, Squamous Cell - pathology
Diagnosis, Differential -
Humans -
Keratosis, Actinic - classification
Keratosis, Actinic - pathology
Medical Illustration -
Skin Neoplasms - classification
Skin Neoplasms - pathology

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