Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Koestenberger, M; Nagel, B; Ravekes, W; Avian, A; Cvirn, G; Rehak, T; Gamillscheg, A.
Reference values of the mitral annular peak systolic velocity (Sm) in 690 healthy pediatric patients, calculation of Z-score values, and comparison to the mitral annular Plane systolic excursion (MAPSE).
ECHOCARDIOGR-J CARD. 2014; 31(9): 1122-1130. Doi: 10.1111/echo.12541
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Führende Autor*innen der Med Uni Graz: Koestenberger Martin
Co-Autor*innen der Med Uni Graz: Avian Alexander; Cvirn Gerhard; Gamillscheg Andreas; Nagel Bert Hermann Philipp; Rehak Thomas
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Abstract:: The mitral annular peak systolic velocity (Sm) is an echocardiographic measurement using tissue Doppler imaging to assess longitudinal left ventricular (LV) systolic function in children and adults. We determined growth-related changes in Sm to establish reference values for the entire pediatric age group. A prospective study was conducted in a group of 690 healthy pediatric patients (age: 1 day-18 years). We determined the effects of age, sex, and body surface area (BSA) on the Sm values. Regression analysis was used to estimate Sm from age, BSA, and sex. In addition, a correlation of normal Sm with normal age-matched values of the M-mode parameter mitral annular plane systolic excursion (MAPSE) was measured. The Sm ranged from a mean of 5.8 cm/sec (Z-score ±2: 3.6-8.0 cm/sec) in the newborn to 11.8 cm/sec (Z-score ±2: 8.5-15.1 cm/sec) in the 18-year-old adolescent. The Sm values showed a positive correlation with age and BSA with a nonlinear course. There was no significant difference in Sm values between females and males. A significant correlation was found between Sm and MAPSE values. Z-scores of Sm values were calculated and percentile charts were established to serve as reference data in patients with congenital heart diseases. © 2014, Wiley Periodicals, Inc.
Find related publications in this database (Keywords): mitral annular peak systolic velocity; left ventricular systolic function; Z-score; pediatric patients; mitral annular plane systolic excursion; reference values