Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Batla, A; Erro, R; Stamelou, M; Schneider, SA; Schwingenschuh, P; Ganos, C; Bhatia, KP.
Patients with scans without evidence of dopaminergic deficit: a long-term follow-up study.
Mov Disord. 2014; 29(14):1820-1825
Doi: 10.1002/mds.26018
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Schwingenschuh Petra
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- Abstract:
- We previously reported on a cohort of dystonic tremor and patients with scans without evidence of dopaminergic deficit (SWEDDs). We aim to report the long-term clinical and imaging follow-up of these patients. Patients with at least 5-year follow-up were included. These patients had an asymmetric arm tremor, a previous diagnosis of Parkinson's disease (PD), and a subsequent normal DaTscan. The imaging and clinical follow-up was done on the clinical basis. Sixteen patients were included. The mean gap between the first and subsequent scans was 5.4 years. Two patients (12.5%) had reduced nigrostriatal uptake on follow-up DaTscan, whereas 14 continued to have normal dopaminergic imaging. This is the longest follow up of patients with asymmetric rest tremor and normal DaT scans (SWEDDs) reported to date. We show here that only a minority of them show reduced striatonigral uptake over long term follow up. © 2014 International Parkinson and Movement Disorder Society.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Dopamine - metabolism
- Dopamine Plasma Membrane Transport Proteins - metabolism
- Dystonic Disorders - diagnosis
- Female -
- Follow-Up Studies -
- Humans -
- Male -
- Middle Aged -
- Parkinson Disease - diagnosis
- Parkinson Disease - physiopathology
- Time -
- Tomography, Emission-Computed, Single-Photon - methods
- Tremor - diagnosis
- Find related publications in this database (Keywords)
- SWEDD
- DaTscan
- Parkinson's disease
- dystonic tremor
- dystonia
- dopamine