Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Pummer, K; Rieken, M; Augustin, H; Gutschi, T; Shariat, SF.
Innovations in diagnostic imaging of localized prostate cancer.
World J Urol. 2014; 32(4):881-890
Doi: 10.1007/s00345-013-1172-6
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Pummer Karl
- Co-Autor*innen der Med Uni Graz
- Augustin Herbert
- Gutschi Thomas
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- In recent years, various imaging modalities have been developed to improve diagnosis, staging, and localization of early-stage prostate cancer (PCa). A MEDLINE literature search of the time frame between 01/2007 and 06/2013 was performed on imaging of localized PCa. Conventional transrectal ultrasound (TRUS) is mainly used to guide prostate biopsy. Contrast-enhanced ultrasound is based on the assumption that PCa tissue is hypervascularized and might be better identified after intravenous injection of a microbubble contrast agent. However, results on its additional value for cancer detection are controversial. Computer-based analysis of the transrectal ultrasound signal (C-TRUS) appears to detect cancer in a high rate of patients with previous biopsies. Real-time elastography seems to have higher sensitivity, specificity, and positive predictive value than conventional TRUS. However, the method still awaits prospective validation. The same is true for prostate histoscanning, an ultrasound-based method for tissue characterization. Currently, multiparametric MRI provides improved tissue visualization of the prostate, which may be helpful in the diagnosis and targeting of prostate lesions. However, most published series are small and suffer from variations in indication, methodology, quality, interpretation, and reporting. Among ultrasound-based techniques, real-time elastography and C-TRUS seem the most promising techniques. Multiparametric MRI appears to have advantages over conventional T2-weighted MRI in the detection of PCa. Despite these promising results, currently, no recommendation for the routine use of these novel imaging techniques can be made. Prospective studies defining the value of various imaging modalities are urgently needed.
- Find related publications in this database (using NLM MeSH Indexing)
- Diagnostic Imaging - methods
- Diagnostic Imaging - trends
- Elasticity Imaging Techniques -
- Humans -
- Magnetic Resonance Imaging -
- Male -
- Neoplasm Staging -
- Prostate - diagnostic imaging
- Prostate - pathology
- Prostatic Neoplasms - diagnosis
- Prostatic Neoplasms - diagnostic imaging
- Prostatic Neoplasms - pathology
- Sensitivity and Specificity -
- Tomography, X-Ray Computed -
- Ultrasonography -
- Find related publications in this database (Keywords)
- Imaging
- Prostate cancer
- TRUS
- MRI