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Hillen, U; Ulrich, M; Alter, M; Becker, JC; Gutzmer, R; Leiter, U; Lonsdorf, A; Messerschmidt, A; Ulrich, C.
[Cutaneous squamous cell carcinoma: a review with consideration of special patient groups].
Hautarzt. 2014; 65(7):590-599
Doi: 10.1007/s00105-013-2734-7
Web of Science
PubMed
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- Co-authors Med Uni Graz
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Becker Jürgen Christian
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- Abstract:
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The incidence of non-melanoma skin cancer (NMSC) is increasing. Squamous cell carcinoma of the skin (SCC) is a tumor of the elderly. Due to the increasing life expectancy, SCC will become more and more frequent in the future. Generally SCC has a favorable prognosis. Standard therapy is microscopically- controlled excision. Therapy of advanced and metastatic SCC is still challenging. Patients with regional lymph node metastasis have ten-year survival rates less than 20%; patients with distant metastases less than 10%. Immunosuppression has been shown to be one of the key prognostic factors for metastasis. The article reviews SCC and focusses on patients being at risk for an unfavorable course.
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Age Distribution -
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Antineoplastic Agents - therapeutic use
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Carcinoma, Squamous Cell - mortality
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Carcinoma, Squamous Cell - pathology
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Carcinoma, Squamous Cell - therapy
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Dermatologic Surgical Procedures - methods
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Humans -
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Incidence -
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Risk Assessment -
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Risk Factors -
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Sex Distribution -
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Skin Neoplasms - mortality
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Skin Neoplasms - pathology
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Skin Neoplasms - therapy
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Survival Rate -
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Non-melanoma skin cancer
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Therapy
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Lymph node metastasis
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Distant metastases
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Immunosuppression