Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Porta, S; Langfort, J; Leitner, G; Teter, A.
Interaction Between Mg and Stress Hormones in Stress - A Short Review
MAGNESIUM, BULL. 1992; 14: 21-23.
Web of Science
- Führende Autor*innen der Med Uni Graz
- Porta Sepp
- Co-Autor*innen der Med Uni Graz
- Leitner Gerhard
- Altmetrics:
- Abstract:
- During stress, the close relationship between Mg metabolism and catecholamine action becomes evident. The reason is mostly the considerable Mg loss which goes hand in hand with stress and makes the effects of substitutive MAH premedication most obvious. Therefore timely MAH substitution prohibited stress induced liverglycogen depletion which in turn cannot trigger additional adrenalin secretion. Moreover, pre-stress MAH substitution directly diminishes medullar adrenaline secretion as well as drastically curbs cortisol increase. The regulators of Mg influenced catecholamine action and catecholamine influenced Mg turnover seem to be the catecholamine receptors, whereby the quantitative participation of alpha and beta types is not yet decided and may well depend upon tissue, species and situations. The time needed for downregulation of those receptors is an important determinant of the sensitivity changes of the system. It allows sudden stresses to unfold all their Mg depleting power, while during long term catecholamine increase tissue sensitivity is diminished by receptor backregulation. This work was supported as a whole by VerlaPharm. Tutzing BRD and partly by a grant of the Austrian Minister of Defense.