Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Portugaller, RH; Kalmar, PI; Deutschmann, H.
The eternal tale of dialysis access vessels and restenosis: are drug-eluting balloons the solution?
J Vasc Access. 2014; 15(6):439-447
Doi: 10.5301/jva.5000271
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- Leading authors Med Uni Graz
- Portugaller Rupert
- Co-authors Med Uni Graz
- Deutschmann Hannes
- Kalmar Peter
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- Abstract:
- In dialysis access fistulas and grafts, percutaneous transluminal angioplasty (PTA) is frequently followed by restenosis development, which results in repeated periodical re-interventions. The technique of drug-eluting balloon (DEB) angioplasty has shown promising results in the treatment of femoropopliteal arteriosclerotic lesions. In contrast to arteriosclerotic arteries, dialysis access vessels host unfavorable hemodynamics due to the direct conduction of high-pressure fluid into a low-pressure system. Hence, the beneficial effect of DEB angioplasty may be limited in this system. However, a first prospective randomized trial on 40 patients with arteriovenous fistula or graft stenoses exhibited a significantly higher 6-month primary patency of the treated lesions after DEB angioplasty than after uncoated balloon angioplasty. Despite such a positive reference, general recommendations regarding the value of DEBs in dialysis access vessels cannot be considered as serious unless large randomized controlled trials have been performed.
- Find related publications in this database (using NLM MeSH Indexing)
- Angioplasty, Balloon - adverse effects
- Angioplasty, Balloon - instrumentation
- Animals -
- Arteriovenous Shunt, Surgical - adverse effects
- Blood Vessel Prosthesis Implantation - adverse effects
- Cardiovascular Agents - administration & dosage
- Coated Materials, Biocompatible -
- Constriction, Pathologic -
- Equipment Design -
- Graft Occlusion, Vascular - diagnosis
- Graft Occlusion, Vascular - etiology
- Graft Occlusion, Vascular - physiopathology
- Graft Occlusion, Vascular - therapy
- Hemodynamics -
- Humans -
- Neointima -
- Recurrence -
- Renal Dialysis -
- Risk Factors -
- Thrombosis - diagnosis
- Thrombosis - etiology
- Thrombosis - physiopathology
- Thrombosis - therapy
- Time Factors -
- Treatment Outcome -
- Vascular Access Devices -
- Find related publications in this database (Keywords)
- Angioplasty
- Balloon
- Dialysis
- Neointima formation
- Paclitaxel
- Vascular graft restenosis