Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Trapp, M; Trapp, EM; Egger, JW; Domej, W; Schillaci, G; Avian, A; Rohrer, PM; Hörlesberger, N; Magometschnigg, D; Cervar-Zivkovic, M; Komericki, P; Velik, R; Baulmann, J.
Impact of mental and physical stress on blood pressure and pulse pressure under normobaric versus hypoxic conditions.
PLoS One. 2014; 9(5):e89005-e89005
Doi: 10.1371/journal.pone.0089005
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- Leading authors Med Uni Graz
- Baulmann Johannes
- Trapp Michael
- Co-authors Med Uni Graz
- Avian Alexander
- Cervar-Zivkovic Mila
- Domej Wolfgang
- Egger Josef Wilhelm
- Hörlesberger Nina
- Komericki Peter
- Rohrer Peter Michael
- Trapp Eva-Maria
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- Abstract:
- Hypobaric hypoxia, physical and psychosocial stress may influence key cardiovascular parameters including blood pressure (BP) and pulse pressure (PP). We investigated the effects of mild hypobaric hypoxia exposure on BP and PP reactivity to mental and physical stress and to passive elevation by cable car. 36 healthy volunteers participated in a defined test procedure consisting of a period of rest 1, mental stress task (KLT-R), period of rest 2, combined mental (KLT-R) and physical task (bicycle ergometry) and a last period of rest both at Graz, Austria (353 m asl) and at the top station Dachstein (2700 m asl). Beat-to-beat heart rate and BP were analysed both during the test procedures at Graz and at Dachstein and during passive 1000 m elevation by cable car (from 1702 m to 2700 m). A significant interaction of kind of stress (mental vs. combined mental and physical) and study location (Graz vs. Dachstein) was found in the systolic BP (p = .007) and PP (p = .002) changes indicating that during the combined mental and physical stress task sBP was significantly higher under hypoxic conditions whereas sBP and PP were similar during mental stress both under normobaric normoxia (Graz) and under hypobaric hypoxia (Dachstein). During the passive ascent in cable car less trivialization (psychological coping strategy) was associated with an increase in PP (p = .004). Our data show that combined mental and physical stress causes a significant higher raise in sBP and PP under hypoxic conditions whereas isolated mental stress did not affect sBP and PP under hypoxic conditions. PP-reaction to ascent in healthy subjects is not uniform. BP reactions to ascent that represents an accumulation of physical (mild hypobaric hypoxia) and psychological stressors depend on predetermined psychological traits (stress coping strategies). Thus divergent cardiovascular reactions can be explained by applying the multidimensional aspects of the biopsychosocial concept.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Blood Pressure - physiology
- Cardiovascular Physiological Phenomena -
- Cross-Over Studies -
- Exercise Test - methods
- Female -
- Heart Rate - physiology
- Humans -
- Hypoxia - physiopathology
- Logistic Models -
- Male -
- Multivariate Analysis -
- Pulse -
- Stress, Psychological - physiopathology
- Surveys and Questionnaires -
- Young Adult -