Medizinische Universität Graz - Research portal
Selected Publication:
Alvarez-Ossorio, L; Kirchner, H; Klüter, H; Schlenke, P.
Low ferritin levels indicate the need for iron supplementation: strategy to minimize iron-depletion in regular blood donors.
Transfus Med. 2000; 10(2):107-112
Doi: 10.1046/j.1365-3148.2000.00239.x
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Schlenke Peter
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Iron deficiency is a common problem in regular blood donors which can be prevented by timely iron supplementation. Consequently, these donors should be supplied with oral iron in good time. We evaluated the need to use ferritin rather than or in addition to haemoglobin to screen iron deficiency in blood donors. To this end, serum ferritin was measured routinely every 10th donation in 632 long-term and 171 first-time donors. Furthermore, donors with ferritin < 15 microg L-1 were supplemented with iron. The supplementation efficiency was assessed by follow-up haemoglobin levels over the course of five donations in blood donors with high donation frequency. Our results showed that ferritin decreases after 10 donations and with the increase of donation frequency. In 26% of regular donors, ferritin levels were < 15 microg L-1 and 12% of them were anaemic due to low haemoglobin. After iron supplementation, haemoglobin was raised rapidly in donors with initially low haemoglobin, and thus donor deferment was never indicated. In conclusion, regular ferritin measurement is a useful indicator for iron depletion in blood donors. Our data suggested the usefulness of ferritin screening in first-time donors and regular donors with low haemoglobin levels within the normal range.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Anemia, Hypochromic - drug therapy Anemia, Hypochromic - epidemiology Anemia, Hypochromic - etiology Anemia, Hypochromic - prevention & control
- Blood Donors -
- Female -
- Ferritins - blood
- Ferritins - epidemiology
- Hemoglobins - analysis Hemoglobins - deficiency
- Humans -
- Iron - administration & dosage Iron - deficiency Iron - therapeutic use
- Male -
- Mass Screening -
- Middle Aged -
- Phlebotomy - adverse effects
- Retrospective Studies -
- Safety -
- Find related publications in this database (Keywords)
- anaemia
- blood donation
- ferritin
- haemoglobin
- iron deficiency