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Kardio
Lipid
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Microb
Lerchbaum, E; Rabe, T.
Vitamin D and female fertility.
Curr Opin Obstet Gynecol. 2014; 26(3):145-150
Doi: 10.1097/GCO.0000000000000065
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
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Lerchbaum Elisabeth
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- Abstract:
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Apart from the well known effects of vitamin D on maintaining calcium homeostasis and promoting bone mineralization, there is some evidence suggesting that vitamin D also modulates human reproductive processes. We will review the most interesting and relevant studies on vitamin D and female fertility published over the past year.
In the past year, several observational studies reported a better in-vitro fertilization outcome in women with sufficient vitamin D levels (≥30 ng/ml), which was mainly attributed to vitamin D effects on the endometrium. One randomized controlled trial found an increased endometrial thickness in women with polycystic ovary syndrome (PCOS) receiving vitamin D during intrauterine insemination cycles. Further, vitamin D supplementation had a beneficial effect on serum lipids in PCOS women. Vitamin D treatment improved endometriosis in a rat model and increased vitamin D intake was related to a decreased risk of incident endometriosis. Vitamin D was also favorably associated with primary dysmenorrhea, uterine leiomyoma, and ovarian reserve in late reproductive aged women.
In women undergoing in-vitro fertilization, a sufficient vitamin D level (≥30 ng/ml) should be obtained. Vitamin D supplementation might improve metabolic parameters in women with PCOS. A high vitamin D intake might be protective against endometriosis.
- Find related publications in this database (using NLM MeSH Indexing)
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Adult -
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Animals -
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Bone Density -
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Dietary Supplements -
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Dysmenorrhea - diet therapy
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Dysmenorrhea - etiology
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Dysmenorrhea - prevention & control
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Endometriosis - diet therapy
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Endometriosis - etiology
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Endometriosis - prevention & control
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Female -
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Fertilization in Vitro -
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Humans -
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Infant, Newborn -
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Infertility, Female - diet therapy
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Infertility, Female - etiology
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Leiomyoma - diet therapy
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Leiomyoma - etiology
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Leiomyoma - prevention & control
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Male -
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Polycystic Ovary Syndrome - diet therapy
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Polycystic Ovary Syndrome - etiology
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Polycystic Ovary Syndrome - prevention & control
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Pregnancy -
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Rats -
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Vitamin D - administration & dosage
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Vitamin D Deficiency - complications
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Vitamin D Deficiency - diet therapy
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Vitamins - administration & dosage
- Find related publications in this database (Keywords)
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endometriosis
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fertility
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in-vitro fertilization
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polycystic ovary syndrome
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vitamin D