Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Chavan, A; Rosenthal, H; Luthe, L; Pfingsten, S; Kutschka, I; Easo, J; Piepenbrock, S; Dapunt, O; Haverich, A; Galanski, M.
Percutaneous interventions for treating ischemic complications of aortic dissection.
EUR RADIOL. 2009; 19(2): 488-494.
Doi: 10.1007/s00330-008-1141-4
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Dapunt Otto Eugen
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- Abstract:
- The aim of this study was to evaluate the role of percutaneous interventions in treating ischemia complicating aortic dissection. Forty-five patients with ischemia complicating aortic dissection were treated by balloon fenestration, true lumen stenting, angioplasty, or thrombolysis. Clinical and laboratory examinations were performed before and after intervention, and at the end of follow-up (median 37 months). Eighteen dissections were acute, 9 sub-acute, and 18 chronic. Mesenterohepatic ischemia resolved in 16 of 18 patients; lactate and SGOT values fell from 2.89 to 1.23 mmol/L (p=0.006) and from 165.9 to 59.7 U/L (p=0.034), respectively. In patients with renal ischemia, creatinine levels fell from 360.1 to 196.3 micromol/L (p=0.007) accompanied by a significant reduction in blood pressure. Limb-threatening ischemia resolved in three of four patients; in 21 claudicants, the mean walking distance improved from 272 to 1,283 m (p=0.001). Spinal ischemia resolved completely or partially in six of eight patients. Adjunctive surgical measures were necessary in six patients. Overall 30-day mortality in the 45 patients was 6.7%; all three deaths were in patients with acute dissections (mortality in this subgroup 16.7%). Ischemia complicating aortic dissection can be effectively treated by percutaneous interventions resulting in good early and mid-term outcomes.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Aneurysm, Dissecting - complications Aneurysm, Dissecting - surgery Aneurysm, Dissecting - therapy
- Angioplasty - methods
- Aortic Aneurysm - complications Aortic Aneurysm - surgery Aortic Aneurysm - therapy
- Contrast Media - pharmacology
- Female -
- Follow-Up Studies -
- Humans -
- Ischemia - therapy
- Kidney - pathology
- Male -
- Middle Aged -
- Stents -
- Tomography, X-Ray Computed - methods
- Treatment Outcome -
- Find related publications in this database (Keywords)
- Ischemia
- Aortic dissection
- Balloon fenestration
- Stent
- Percutaneous intervention