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Böck, K; Pschaid, C; Topakian, R; Stieglbauer, K; Doppler, S; von Oertzen, JT; Pichler, R.
Mononeuritis multiplex: association with infectious condition and familial background in a tropical environment: a case report.
Wien Klin Wochenschr. 2014; 126 Suppl 1(4):S42-S45
Doi: 10.1007/s00508-014-0504-x
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- Co-Autor*innen der Med Uni Graz
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Pichler Robert
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- Abstract:
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Mononeuritis multiplex is characterized by an asymmetric pattern with affection of the peripheral nervous system; this form of polyneuropathy is often seen in non-systemic vasculitis. We present a case of multiplex neuropathy in a patient with histologicaly verified Hailey-Hailey disease. With the exception of this comorbidity--in its characteristic form presenting additionally with a superinfected subdermal node--we did not find any other possible etiologic factor possibly causative of multiplex neuritis. The diagnosis was confirmed by electrophysiological testing. To our knowledge, this is the first case report indicating a possible relationship between Hailey-Hailey disease and multiplex neuritis. There exists only one related study in the literature, which was conducted in Columbia--our patient's home country. This study delineates a clinically similar dermal disease (pemphigus foliaceus) in patients from rural Colombia (El Bagre). The authors detected anti-neuronal antibodies which were interpreted to be responsible for the pathognomonic burning sensations.
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Adult -
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Analgesics - therapeutic use
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Anti-Inflammatory Agents - therapeutic use
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Anti-Inflammatory Agents -
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Anti-Inflammatory Agents -
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Humans -
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Male -
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Mononeuropathies - diagnosis
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Mononeuropathies - drug therapy
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Mononeuropathies - genetics
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Pemphigus, Benign Familial - diagnosis
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Pemphigus, Benign Familial - drug therapy
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Pemphigus, Benign Familial - genetics
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Treatment Outcome -
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Tropical Climate -
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Polyneuropathy
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Mononeuritis multiplex
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Hailey-Hailey disease
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Pemphigus foliaceus
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Vasculitis