Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Orlic, D; Smerdelj, M; Kolundzic, R; Bergovec, M.
Lower limb salvage surgery: modular endoprosthesis in bone tumour treatment.
Int Orthop. 2006; 30(6):458-464
Doi: 10.1007/s00264-006-0193-9
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- Abstract:
- We retrospectively analysed 90 patients who underwent "en bloc" resection and modular endoprosthesis reconstruction in the lower limbs between 1987-2003. After proximal femur resection, reconstruction was performed with a modular endoprosthesis by Howmedica (KFTR, designed by Kotz) and modular revision endoprosthesis by W. Link or Lima-Lto (Revision system, designed by Wagner). The knee joint was reconstructed with a modular endoprosthesis (Howmedica, KFTR designed by Kotz) after distal femur or proximal tibia resection. Malignant bone tumours were present in 58 patients (64.5%), benign tumours in 16 (17.8%), metastases in 8 (8.9%), tumour-like lesions in 4 (4.4 %) and non-tumour-related destruction of the femur in 4 patients (4.4%). High-grade tumours were found in the majority of malignant bone tumours (70.7%). Treatment complications, which occurred in 26 patients, were: local recurrence of the tumour, deep infection, acetabular destruction following hemiarthroplasty, recurrent dislocations of endoprosthesis, periprosthetic fracture and hardware problems. In total, 23 patients (25.6%) died due to tumours. Endoprostheses should be considered as a treatment of choice for bone tumours in the hip and knee joint region. Advances in limb salvage surgery are, and will long continue to be, a great challenge for orthopaedic oncologists of the 21st century.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Arthroplasty, Replacement, Hip -
- Arthroplasty, Replacement, Knee -
- Artificial Limbs -
- Bone Cements - therapeutic use
- Bone Nails -
- Bone Neoplasms - rehabilitation Bone Neoplasms - surgery
- Child -
- Female -
- Fractures, Spontaneous - therapy
- Humans -
- Limb Salvage - adverse effects Limb Salvage - instrumentation Limb Salvage - methods
- Male -
- Middle Aged -
- Prosthesis Design -
- Prosthesis Failure -
- Retrospective Studies -