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SHR Neuro Cancer Cardio Lipid Metab Microb
Pokan, R; Von Duvillard, SP; Ludwig, J; Rohrer, A; Hofmann, P; Wonisch, M; Smekal, G; Schmid, P; Pacher, R; Bachl, N.
Effect of high-volume and -intensity endurance training in heart transplant recipients.
Med Sci Sports Exerc. 2004; 36(12):2011-2016
Doi: 10.1249/01.MSS.0000147630.71210.06
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- Co-authors Med Uni Graz
- Wonisch Manfred
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- Abstract:
- BACKGROUND: A recommended component of heart transplant recipients (HTR) is endurance-oriented exercise therapy. However, the trainability of HTR after transplantation is vague. We examined the effect of high-volume and -intensity exercise training on exercise performance in HTR, compared with HTR undergoing regular rehabilitation training, and sedentary healthy subjects (SHS). METHODS: We studied four groups of individuals; of those, three groups were HTR. Subjects were a regularly trained HTR group of denervated (HTR-D; N = 15), reinnervated (HTR-R; N = 26) hearts, a high-volume and -intensity endurance-training group (training time 7-20 h.wk(-1); HTR-ET; N = 12), and a group of sedentary healthy subjects (SHS; N = 21). All participants performed cardiopulmonary exercise testing. RESULTS: The HTR-ET achieved a significantly higher performance (255 +/- 47 W, VO(2max) of 45.2 +/- 6.9 mL.kg(-1).min(-1)) in contrast to all other groups (HTR-D: 119 +/- 17 W, VO(2max) of 17.4 +/- 4.5 mL.kg(-1).min(-1); HTR-R: 119 +/- 17 W, VO(2max) of 16.9 +/- 3.7 mL.kg(-1).min(-1); SHS: 184 +/- 19 W, VO(2max) of 35.0 +/- 6.9 mL.kg(-1).min(-1)). The HR at maximal power output in the HTR-ET was 169 +/- 17 bpm and similar to SHS (164 +/- 17 bpm), but significantly higher than HTR-D (125 +/- 16) and HTR-R (142 +/- 10). Maximal lactate concentration (LAmax) of HTR-ET was 9.9 +/- 2.2 mmol.L(-1), comparable to SHS (9.2 +/- 2.1 mmol.L(-1)), and significantly higher than HTR-D (5.5 +/- 1.5 mmol.L(-1)) and HTR-R (5.1 +/- 1.0 mmol.L(-1)). CONCLUSIONS: Data suggest that HTR can perform high-volume and -intensity exercise training, reaching exercise performance comparable to or even exceeding values of sedentary or moderately trained healthy subjects.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Exercise Therapy -
- Heart Transplantation - rehabilitation
- Humans - rehabilitation
- Lactic Acid - blood
- Male - blood
- Middle Aged - blood
- Oxygen Consumption - blood
- Physical Endurance - blood
- Treatment Outcome - blood
- Find related publications in this database (Keywords)
- cardiac transplantation
- exercise performance
- respiratory gas exchange
- blood lactate concentration