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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Wech, T; Pickl, W; Tran-Gia, J; Ritter, C; Beer, M; Hahn, D; Köstler, H.
Whole-heart cine MRI in a single breath-hold--a compressed sensing accelerated 3D acquisition technique for assessment of cardiac function.
Rofo. 2014; 186(1):37-41
Doi: 10.1055/s-0033-1350521
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- Co-authors Med Uni Graz
- Beer Meinrad
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- Abstract:
- The aim of this study was to perform functional MR imaging of the whole heart in a single breath-hold using an undersampled 3 D trajectory for data acquisition in combination with compressed sensing for image reconstruction. Measurements were performed using an SSFP sequence on a 3 T whole-body system equipped with a 32-channel body array coil. A 3 D radial stack-of-stars sampling scheme was utilized enabling efficient undersampling of the k-space and thereby accelerating data acquisition. Compressed sensing was applied for the reconstruction of the missing data. A validation study was performed based on a fully sampled dataset acquired by standard Cartesian cine imaging of 2 D slices on a healthy volunteer. The results were investigated with regard to systematic errors and resolution losses possibly introduced by the developed reconstruction. Subsequently, the proposed technique was applied for in-vivo functional cardiac imaging of the whole heart in a single breath-hold of 27 s. The developed technique was tested on three healthy volunteers to examine its reproducibility. By means of the results of the simulation (temporal resolution: 47 ms, spatial resolution: 1.4 × 1.4 × 8 mm, 3 D image matrix: 208 × 208 × 10), an overall acceleration factor of 10 has been found where the compressed sensing reconstructed image series shows only very low systematic errors and a slight in-plane resolution loss of 15 %. The results of the in-vivo study (temporal resolution: 40.5 ms, spatial resolution: 2.1 × 2.1 × 8 mm, 3 D image matrix: 224 × 224 × 12) performed with an acceleration factor of 10.7 confirm the overall good image quality of the presented technique for undersampled acquisitions. The combination of 3 D radial data acquisition and model-based compressed sensing reconstruction allows high acceleration factors enabling cardiac functional imaging of the whole heart within only one breath-hold. The image quality in the simulated dataset and the in-vivo measurement highlights the great potential of the presented technique for an efficient assessment of cardiac functional parameters. © Georg Thieme Verlag KG Stuttgart · New York.
- Find related publications in this database (using NLM MeSH Indexing)
- Algorithms -
- Breath Holding -
- Cardiac-Gated Imaging Techniques - methods
- Data Compression - methods
- Healthy Volunteers -
- Heart Function Tests - methods
- Humans -
- Image Enhancement - methods
- Image Interpretation, Computer-Assisted - methods
- Imaging, Three-Dimensional - methods
- Magnetic Resonance Imaging, Cine - methods
- Reproducibility of Results -
- Sensitivity and Specificity -
- Ventricular Function, Left - physiology
- Find related publications in this database (Keywords)
- heart
- MR imaging
- MR functional imaging