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Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Halwachs, B; Höftberger, J; Stocker, G; Snajder, R; Gorkiewicz, G; Thallinger, GG.
High-Troughput Characterization and Comparison of Microbial Communities.
Biomed Tech (Berl). 2013; 58 Suppl 1(1): Doi: 10.1515/bmt-2013-4312
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Leading authors Med Uni Graz
Halwachs-Wenzl Bettina
Study Group Members Med Uni Graz:
Gorkiewicz Gregor
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Abstract:
The analysis of the huge amount of generated sequence data as well as pyrosequencing noise and chimeric sequences originating from PCR amplification pose a considerable challenge to the individual researcher in doing microbiome studies. The unbiased knowledge about microbial community composition and -structure as well as the interactions with the human host microbiome can give important insights into its role in human health and disease. Here we introduce SnoWMAn, the high-throughput microbiome analysis pipeline and additionally investigate the effects of sequencing noise on non denoised and data denoised using two different approaches.

Find related publications in this database (Keywords)
Next Generation Sequencing
Community Composition Analysis
Denoising
OTU inflation
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