Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kueh, JT; Choi, KW; Williams, GM; Moehle, K; Bacsa, B; Robinson, JA; Brimble, MA.
Synthesis of a 6,6-spiroketal amino acid and its incorporation into a peptide turn sequence using solid-phase peptide synthesis.
Chemistry. 2013; 19(12): 3807-3811.
Doi: 10.1002/chem.201204546
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Bacsa Bernadett
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- Abstract:
- Spiropins for SPPS: The rigid structure of an anomerically stabilised spiroketal motif enables the appendage of substituents in a fixed conformation. To assess the ability of a spiroketal motif to induce a turn structure and participate in solid-phase peptide synthesis (SPPS), an Fmoc-spiroketal amino acid was synthesised and incorporated into a spiroketal-containing cyclic peptide.
- Find related publications in this database (using NLM MeSH Indexing)
- Amino Acid Sequence -
- Amino Acids - chemical synthesis Amino Acids - chemistry
- Furans - chemical synthesis Furans - chemistry
- Models, Molecular -
- Molecular Sequence Data -
- Nuclear Magnetic Resonance, Biomolecular -
- Peptides - chemical synthesis
- Solid-Phase Synthesis Techniques - methods
- Spiro Compounds - chemical synthesis Spiro Compounds - chemistry
- Find related publications in this database (Keywords)
- amino acids
- peptidomimetics
- reverse turns
- solid-phase peptide synthesis
- spiroketals